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  • About COPSAC
    • About
    • Organization Diagram
    • Board of Directors
    • Research team
    • Location
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    • Open positions
  • COPSAC cohorts
    • COPSAC2000 cohort
    • COPSAC2010 cohort
    • COPSACSEVERE cohort
    • COPSACACUTE cohort
    • Methods
    • Data overview
      • COPSAC2000 Clinic
      • COPSAC2000 Exposures
      • COPSAC2000 Omics
      • COPSAC2000 Biobank
      • COPSAC2010 Clinic
      • COPSAC2010 Exposures
      • COPSAC2010 Omics
      • COPSAC2010 Biobank
  • Dissemination
    • Theses
    • Literature for parents
  • Research Projects
    • RestoreGut
    • COPSYCH Research Alliance
    • HEDIMED Consortium
    • EDIAQI Consortium
    • EAGLE Consortium
    • EarlyVir
  • Strategy
  • ‌

Home

  • About COPSAC
    • Research team
      • Hans Bisgaard
      • Mette Damgaard Nielsen
      • Katrine Grau
      • Birgit Nielsen
      • Marianne Mikkelsen
      • Ulrik Ralfkiaer
      • Connie Albinski
      • Dorte Andersen
      • Dion Aagaard-Hansen
      • Michael Westenholz
      • Brian Vegas
      • Alma Pedersen
      • Bo Chawes
      • Jakob Stokholm
      • Nadja Vissing
      • Klaus Bønnelykke
      • Johannes Waage
      • Tarun Ahluwalia
      • Anna Thysen
      • Morten Rasmussen
      • Johan de Rooi
      • Leon Jessen
      • Helene Wolsk
      • Henrik Hallas
      • Tine Pedersen
      • Rebecca Vinding
      • Sunna Thorsteinsdottir
      • Astrid Sevelsted
      • Lambang Arianto
      • Jonathan Thorsen
      • Nadia Fink
      • Asja Kunøe
      • Sarah Pedersen
      • Mathias Hansen
      • Sine Rossen
      • Pia Nørrisgaard
      • Louise Monnerup
      • Pernille Fjordholt
      • Lena Vind
      • Hanne Nissen
      • Britta Hansen
      • Simone Hansen
      • Ann-Marie Schoos
      • Kristoffer Linder
      • Michael Lofvall
      • Martin Mortensen
      • Ni Wang
      • Christian Carlsson
      • Malene Rosenberg
      • Emil Christensen
      • Mia Bjørg Olsen
      • Hedda Løvenhøj
      • Jens Heller Frederiksen
      • Pernille Tegner Fjordholt
      • Shiraz Shah
      • Lærke Sass
      • Mathis Hjelmsø
      • Line Reinvard
      • Nilo Følsgaard
      • Daniela Rago
      • Anders Eliasen
      • Nicklas Brustad
      • Line Reinvard
      • Rebekka Søgaard
      • Casper Pedersen
      • Rebekka Søgaard
      • Jenni Lehtimäki
      • Nicklas Brustad
      • Julie Rosenberg
      • Gözde Gürdeniz
      • Mads Nørregaard
      • Caroline Kleis
      • Laura Hesselberg
      • Rikke Sunde
      • Tamsin Redgwell
      • Mathias Elsner Melgaard
      • Signe Kjeldgaard Jensen
      • Maibritt Clausen
      • Sofie Ingwersen
      • Matteo Soverini
      • Marie-Louise Hjuler
      • Mie Liljendahl
      • Michelle Pedersen
      • Sarah Brandt
      • Julie Kyvsgaard
      • David Horner
      • Matthew Stevenson
      • Amelie Fritz
      • Luo Yang
      • Jesper Rasch
      • Frederikke Rosenvinge Skov
      • Clara Vilhelmsen
      • Benthe Vink
      • Danielle Erbs-Hansen
      • Min Kim
      • Signe Hansen
      • Nanna Larsson
      • Trine Mølbæk
      • Kasper Fischer-Rasmussen
      • Alex Hemmingsen
      • Eric Qing Zou
      • Cristina Leal Rodríguez
      • Kristina Aagaard
      • Maria Hernandez Lorca
      • Emil Høj Christiansen
      • Thomas Rosenbom
      • Iva Šunić
      • Liang Chen
      • Casper Sahl Poulsen
      • Mina Ali
      • Tingting Wang
      • Ann-Sofie Colding Lund
      • Nina Flensborg
      • Jay Jiang
      • Tamo Sultan
      • Camilla Grube
      • Michael Widdowson
      • Alexandra Dalgas-Madsen
      • Frederikke Østergaard
      • Rikke Brandt Bangsgaard
      • Johannes Wilm
      • Parvaneh Ebrahimi
      • Zhi Ye
      • Zhuobing Peng
      • Michael Forsmann
      • Urvish Trivedi
      • Beatriz Gomes
      • Kathrine Jacaob
      • Camille Ramm-Larsen
      • Ulrikka Boulund
      • Helena Hermansen
      • Marie Louise Jahn
      • Dorthe Klitmose Dahlstrøm
      • Kaare Tranæs
      • Amalie Klein-Petersen
      • Frida Sidenius Jensen
      • Lars Hjortshøj
      • Jay Jiang
      • Karen Hansen
      • Camilla Grube
      • Jonathan Groot
    • Location
    • Funding
    • Sponsors
    • Contact
    • Open positions
      • Prægraduat Næstved
      • Research Manager
      • Prægraduat Næstved
      • Forskningsassistent til klinisk børneforskning
      • PhD opslag COPSAC
      • Postdoc in early life human virome
      • PhD opslag COPSAC
      • Postdoc position in early life human virome
      • PhD or Postdoc position within mechanisms and shared origin of immune mediated diseases
      • PhD position in bioinformatics and human genetics
      • IT – studenter hjælp til forskningscenter søges
      • Forskningsassistent søges til klinisk børneforskning
      • Metabolomics postdoc position
      • Softwareudvikler / programmør
      • PhD opslag COPSAC
      • IT-udvikler og supporter med bredt kendskab til Django og Python
      • Postdoctoral position at COPSAC
      • Postdoctoral position at COPSAC
      • Postdoctoral position at COPSAC
      • Forskningsassistent til klinisk børneforskning
      • Metabolomics research scientist
      • Full-stack Python developer
      • DXA skanningsuddannet til klinisk børneforskning
      • Forskningsassistent til klinisk børneforskning
      • PhD projekter indenfor Børneastma eller relaterede sygdomme
      • Forskningsassistent til klinisk børneforskning
      • Postdoc position in early life human virome
      • PhD fellowship in computational life science
      • Forskningsassistent til klinisk børneforskning
      • Ph.d.-projekt omhandlende det tidlige miljøs betydning for børneeksem
      • Junior Developer
      • PhD projekt
      • Kommunikationsmedarbejder med fokus på videnskabsformidling, hjemmeside og sociale medier
      • Postdoc for Funding and Strategy
      • PhD student to explore the acute airway microbiome in childhood asthma
      • Forskningsassistent til klinisk børneforskning
    • Organization Diagram
    • Scientific visitors
      • Andrew Bush
      • Johan de Jongste
      • Frederik-Jan van Schooten
      • Bengt Björkstén
      • David Strachan
      • John Henderson
      • Erika von Mutius
    • Research team (new look)
    • Research Students
    • Sponsors
    • Expatriates
    • Board of Directors
      • Randi Poulsen
      • Søren Pedersen
      • Preben-rudiengaard
      • Peter Kurstein
      • Kirsten Andersen
      • Erik Ove
      • Michael Christiansen
    • Persondatapolitik
    • COPSAC Alumni
    • Research Students
    • Hall of Fame
    • COPSAC Alumni
  • Methods
  • Dissemination
    • Research Awards and Honors
    • Publications
    • Theses
      • 2015 Ann-Marie Malby Schoos, MD PhD
        • Thesis_2015_Ann-Marie_Schoos
      • 2014 Marie Kragh, MSc PhD
        • Thesis_2014_Marie-Kragh.pdf
      • 2014 Eskil Kreiner-Møller, MD PhD
        • Thesis_2014_Eskil-Kreiner-Moller
      • 2014 Nadja Hawwa Vissing, MD PhD
        • Thesis_2014_Nadja-Vissing
      • 2014 Anna Hammerich Thysen, Msc PhD
        • Thesis_2014_Anna-Thysen
      • 2013 Charlotte Giwercman Carson MD, PhD
        • Thesis_2013_Charlotte-Giwercman
      • 2013 Anne Louise Bischoff MD, PhD
        • Thesis_2013_Anne-Bischoff
      • 2012 Louise Pedersen, MD, PhD
        • Thesis_2012_Louise-Pedersen
      • 2012 Jakob Stokholm, MD, PhD
        • Thesis_2012_Jakob-Stokholm
      • 2012 Nilofar Følsgaard, MD, PhD
        • Thesis_2012_Nilo-Foelsgaard
      • 2011 Martin Brasholt, MD, PhD
        • Thesis_2011_Martin-Brasholt
      • 2011 Bo Chawes, MD, PhD
        • Thesis_2011_Bo-Chawes
      • 2010 Klaus Bønnelykke, MD, PhD
        • Thesis_2010_Klaus-Bonnelykke
      • 2010 Porntiva Poorisrisak, MD, PhD
        • Thesis_2010_Porntiva-Poorisrisak
      • 2009 Mette N Hermansen, MD, PhD
        • Thesis_2009_Mette-Hermansen
      • 2006 Liselotte B Halkjær, MD, PhD
        • Thesis_2006_Liselotte-Halkjær
      • 2006 Birgitte Boysen Kjær, MD, PhD
      • 2004 Lotte Loland, MD, PhD
        • Thesis_2004_Lotte-Loland
      • 2002 Frederik F Buchvald, MD, PhD
        • Thesis_2002_Frederik-Buchvald
      • 1999 Marianne Stubbe Østergaard, MD, PhD
      • 1993 Jytte Fogh, MD, PhD
      • 2017 Elín Bjarnadóttir, MD PhD
      • 2017 Helene Wolsk, MD
      • 2017 Tine Marie Pedersen, MD
      • 2017 Astrid Sevelsted, MSc
      • 2017 Rebecca Kofod Vinding, MD
      • 2019 Lambang Arianto, MD
      • 2018 Henrik Hallas, MD
      • 2018 Jonathan Thorsen, MD
      • 2018 Nadia Rahman Fink, MD
      • 2019 Christian Carlsson, MD
      • 2019 Christian Carlsson, MD
      • 2019 Ni Wang, MD
      • 2021 Sarah Nørgaard – MSc
      • 2020 Asja Kunøe – MD
      • 2021 Nicklas Brustad – MD
      • 2021 Anders Eliasen – MSc
      • 2021 Lærke Sass – MD
      • 2022 Pia Nørrisgaard – MSc
      • 2022 Emil Christensen – MD
      • 2023 Rikke Sunde – MD
      • 2023 Julie Kyvsgaard – MD
      • 2024 Yang Luo – MSc
      • 2024 Julie Rosenberg – MD
      • 2024 Christina Poulsen – MSc
      • 2024 Parisa Mohammadzadeh – MD
      • 2024 Signe Jensen – MD
      • 2024 David Horner – MD
      • 2025 Liang Chen
      • 2025 Sarah Brandt
    • Literature for parents
      • Asthma in Young Children
      • Asthma in children at the age of 7-18 years
      • Topical Steriods for Children with Asthma
    • News
      • Exploring the role of bacteria in allergies and asthma
      • Bacteria and asthma
    • DMSc theses
      • 2006 Kim G Nielsen, MD, DMSci
        • Thesis_DMSci_2006_Kim-Nielsen
      • 2002 Bent Helmuth Klug, MD, DMSci
        • Thesis_DMSci_2002_Bent-Klug
      • 2016 Bo Chawes, MD, PhD, DMSci
        • Thesis_DMSci_2016_Bo-Chawes
    • Hall of Fame
    • Newsletter
      • COPSAC informationsaften
    • Publications
  • Research Strategy
    • Bioequivalence
    • Author guidelines
  • COPSAC cohorts
    • COPSAC2000 cohort
    • COPSAC2010 cohort
    • Biobank Inventory
    • COPSAC2010 Environmental exposures
    • COPSAC2000 Environmental exposures
    • COPSAC2010 Biobank
    • COPSAC2000 Biobank
    • COPSAC2000 Clinic
    • COPSAC2010 Clinic
    • COPSAC2010 Omics
    • COPSAC2000 Omics
    • COPSAC2000 Biomarkers
    • COPSAC2010 Biomarkers
    • COPSAC severe cohort
    • COPSAC acute cohort
  • Research Clusters
    • EarlyVir
    • DSF
    • Lundbeck
    • DPAC
    • EAGLE Consortium
    • U-BIOPRED
    • COPSYCH
    • HEDIMED Consortium
    • EDIAQI Consortium
    • RestoreGut
  • Symposia
    • COPSAC Retreat summer 2013
    • ESOF 2014
    • COPSAC retreat summer 2015
    • Sterk visit 2015
    • COPSAC day winter 2015
    • Henderson & Jongste visit 2016
    • Ober visit 2016
  • ERC Grant Bo Chawes

Copsac’s mission is to improve prevention of chronic inflammatory diseases, diagnosis and treatment of childhood asthma. It is our goal to be an international centre of excellence.

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COPSAC
Cohorts

Longitudinal clinical mother-child cohorts

COPSAC2000

COPSAC2010

COPSACSEVERE

COPSACACUTE

Research Strategy

Translational clinical research approach based on long-term studies  of mother-child cohorts with deep phenotyping and exposure assessment

Available Data

Collaborations are invited on our COPSAC cohort data:
Clinical assessments, exposures, OMICS analyses and biological samples

COPSAC videos

Copsac the movie, whiteboard presentations, patient cases and more

Publications

Complete list of COPSAC’s peer-reviewed papers

Center Awards

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COPSAC Follow

COPSAC is a clinical research unit for pediatric asthma research with the aim of developing evidence-based prevention strategies.

COPSAC_com
copsac_com COPSAC @copsac_com ·
27 Oct 2023

New results from the microbiome group on infant airway microbiome and asthma!

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copsac_com COPSAC @copsac_com ·
24 May 2023

In a new study we found that high levels of 25(OH)D in early childhood were associated with a reduced risk of AD, allergy, asthma exacerbations and infections. Our findings suggest vitamin D as an important micronutrient in early childhood.

https://onlinelibrary.wiley.com/doi/abs/10.1111/all.15759

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copsac_com COPSAC @copsac_com ·
9 May 2023

David Horner MD @DavidHo35999694 presents his study from the COPSAC2010 cohort, which showed that supplementation with fish oil in pregnant women reduced the risk of gastroenteritis (vomiting/diarrhea) for their children.

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copsac_com COPSAC @copsac_com ·
1 May 2023

Wow - a very popular science youtube channel picked up our recent paper. Thanks a lot for the interest and communicating our findings in a fun and engaging way!

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Hans Bisgaard has passed away on September 8th 2022

Professor of paediatrics, MD Hans Bisgaard has unexpectedly and far too soon passed away aged 67 after a long and impressive research career.
In 2002, Hans established a translational research center – the COpenhagen Prospective Studies on Asthma in Childhood (COPSAC) – where clinical and basic researchers collaborated, long before it became the norm elsewhere. Here Hans also established the COPSAC cohorts with 1,111 families and children. Hans had great respect for the families who dedicated themselves to research, which he often talked about.
Hans will be remembered as a pioneer in his field of research, where he has made a huge difference for children with asthma and has moved the field of scientific research forward. He will be missed by his patients, his current and former colleagues, everyone he has mentored, as well as all the many national and international partners he has had throughout his long career.
In honor of Hans’ memory

Research Strategy

The COPSAC study with its translational clinical research approach based on long-term studies of mother-child cohorts with deep phenotyping and exposure assessment, combined with genotyping and sequencing of the microbiome, insight into the genetic regulation of basic biological processes, and state-of-the-art systems biology methods holds the promise to improve our understanding of the processes causing disease in individual patients and the interaction between heredity and environment.

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Methods

COPSAC has developed and refined a number of methods used to diagnose and monitor asthma in children. Here we present a selection of the principal methods used at COPSAC.

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Drawings by Heather Spears


CONTACT

COPSAC
Copenhagen Prospective Studies on Asthma in Childhood
Copenhagen University Hospital, Herlev-Gentofte
phone +45 3867 7360
contact@copsac.com
COPSAC • Copenhagen University Hospital, Herlev-Gentofte • Denmark © 2023
  • About COPSAC
    • About
    • Organization Diagram
    • Board of Directors
    • Research team
    • Location
    • Funding
    • Logo
    • Open positions
  • COPSAC cohorts
    • COPSAC2000 cohort
    • COPSAC2010 cohort
    • COPSACSEVERE cohort
    • COPSACACUTE cohort
    • Methods
    • Data overview
      • COPSAC2000 Clinic
      • COPSAC2000 Exposures
      • COPSAC2000 Omics
      • COPSAC2000 Biobank
      • COPSAC2010 Clinic
      • COPSAC2010 Exposures
      • COPSAC2010 Omics
      • COPSAC2010 Biobank
  • Dissemination
    • Theses
    • Literature for parents
  • Research Projects
    • RestoreGut
    • COPSYCH Research Alliance
    • HEDIMED Consortium
    • EDIAQI Consortium
    • EAGLE Consortium
    • EarlyVir
  • Strategy
  • ‌
COPSAC