The COPSAC2000 cohort
The COPSAC2000 cohort is a prospective clinical mother-child cohort study of 411 children of asthmatic mothers. The study is designed to assess gene-environment interactions in the origin of atopic diseases with an aim to identify early-life exposures that can be modified to improve preventive strategies. The children attend the COPSAC clinical research unit from birth till adolescence at scheduled clinical investigations according to standard operating procedures. Additional visits are arranged at onset of any respiratory or skin symptom.