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Copenhagen Prospective Studies on Asthma in Childhood, COPSAC has participated in a large international consortium named MiBioGen which aimed at identifying genetic factors involved in shaping the composition of the human gut microbiome by analyzing the common genetic factors that influence the composition of the human gut microbiome in more than 18,000 people. The studyRead more

In a genetic study of 2866 Danish children aged 0-6 years with severe asthma attacks, researchers from COPSAC in collaboration with researchers from DTU, SSI and several American research groups have been able to identify a new asthma gene called FUT2 as in interaction with the AB0 blood type increases the risk of childhood asthmaRead more

New study highlights long-term perturbations of the early gut microbiome as a possible mechanism for the observed association between caesarean section and increased risk of developing asthma The prevalence of caesarean section has increased globally in recent decades. While the World Health Organisation suggests that the procedure should be performed in less than 15% ofRead more

  by Mette Haagen Marcussen In a new study, researchers from DTU and the research unit for childhood asthma COPSAC have—as the first in the world—shown that immune system responses in children as young as 18 months can be used to predict the risk of them developing intermittent or persistent asthma. The method used byRead more

BMJ September 2018 Effect of fish oil supplementation in pregnancy on bone, lean, and fat mass at six years: randomised clinical trial. Vinding RK, Stokholm J, Sevelsted A, Sejersen T, Chawes BL, Bønnelykke K, Thorsen J, Howe LD, Krakauer M, Bisgaard H. Abstract OBJECTIVE: To examine the effect of supplementation with n-3 long chain polyunsaturatedRead more

Researchers from COPSAC, Herlev and Gentofte Hospital and Harvard University have joined forces to study what mechanisms are important to prevent the development of asthma. The study has received funding of 2 million dollars from the renowned National Institute of Health (NIH) and the project starts in the fall. Asthma is a very common causeRead more

Nat. Genet. August 2018 Effect of fish oil supplementation in pregnancy on bone, lean, and fat mass at six years: randomised clinical trial. Waage J, Standl M, Curtin JA, Jessen LE, Thorsen J, Tian C, Schoettler N; 23andMe Research Team; AAGC collaborators, Flores C, Abdellaoui A, Ahluwalia TS, Alves AC, Amaral AFS, Antó JM, ArnoldRead more

Copenhagen Health Science Partners, June 29th, 2018 The research academy Copenhagen Health Science Partners launches four new excellent research partnerships focussing on paediatric asthma, cancer, osteoarthritis and paediatric infections. The ambitious partnerships between the Capital Region of Denmark and the University of Copenhagen aim to contribute with knowledge and results of benefit to more patients.Read more

J Allergy Clin Immunol. May 2018 Cat exposure in early life decreases asthma risk from the 17q21 high-risk variant Jakob Stokholm, Bo L. Chawes, Nadja Vissing, Klaus Bønnelykke, HansBisgaard Author information Abstract Background Early-life exposure to cats and dogs has shown diverging associations with childhood asthma risk, and gene-environment interaction is one possible explanation. ObjectivesRead more

Nat. Commun. January 2018 Maturation of the gut microbiome and risk of asthma in childhood. Stokholm J, Blaser MJ, Thorsen J, Rasmussen MA, Waage J, Vinding RK, Schoos AM, Kunøe A, Fink NR, Chawes BL, Bønnelykke K, Brejnrod AD, Mortensen MS, Al-Soud WA, Sørensen SJ, Bisgaard H. Abstract The composition of the human gut microbiomeRead more