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Author Pedersen, T.M.; Mora-Jensen, A.-R.C.; Waage, J.; Bisgaard, H.; Stokholm, J. url  doi
openurl 
  Title Incidence and Determinants of Ventilation Tubes in Denmark Type Journal Article
  Year (down) 2016 Publication PloS one Abbreviated Journal PLoS One  
  Volume 11 Issue 11 Pages e0165657  
  Keywords  
  Abstract BACKGROUND AND OBJECTIVES: Many children are treated for recurrent acute otitis media and middle ear effusion with ventilation tubes (VT). The objectives are to describe the incidence of VT in Denmark during 1997-2011 from national register data, furthermore, to analyze the determinants for VT in the Copenhagen Prospective Studies on Asthma in Childhood2010 (COPSAC2010) birth cohort. METHODS: The incidence of VT in all children under 16 years from 1997-2011 were calculated in the Danish national registries. Determinants of VT were studied in the COPSAC2010 birth cohort of 700 children. RESULTS: Nationwide the prevalence of VT was 24% in children aged 0 to 3 three years, with a significant increase over the study period. For all children 0-15 years, the incidence of VT was 35/1,000. In the VT population, 57% was male and 43% females. In the COPSAC2010 birth cohort, the prevalence of VT during the first 3 years of life was 29%. Determinants of VT were: maternal history of middle ear disease; aHR 2.07, 95% CI [1.45-2.96] and siblings history of middle ear disease; aHR 3.02, [2.11-4.32]. Paternal history of middle ear disease, presence of older siblings in the home and diagnosis of persistent wheeze were significant in the univariate analysis but the association did not persist after adjustment. CONCLUSION: The incidence of VT is still increasing in the youngest age group in Denmark, demonstrating the highest incidence recorded in the world. Family history of middle ear disease and older siblings are the main determinants for VT.  
  Address Department of Pediatrics, Naestved Hospital, Naestved; Denmark  
  Corporate Author Thesis  
  Impact Factor 03,234 First Author Pedersen, T.M. Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Senior Author Stokholm, J.  
  ISSN 1932-6203 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:27875554 Approved no  
  Call Number Serial 330  
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