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Author Garn, H.; Bahn, S.; Baune, B.T.; Binder, E.B.; Bisgaard, H.; Chatila, T.A.; Chavakis, T.; Culmsee, C.; Dannlowski, U.; Gay, S.; Gern, J.; Haahtela, T.; Kircher, T.; Muller-Ladner, U.; Neurath, M.F.; Preissner, K.T.; Reinhardt, C.; Rook, G.; Russell, S.; Schmeck, B.; Stappenbeck, T.; Steinhoff, U.; van Os, J.; Weiss, S.; Zemlin, M.; Renz, H. url  doi
  Title Current concepts in chronic inflammatory diseases: Interactions between microbes, cellular metabolism, and inflammation Type Journal Article
  Year (down) 2016 Publication The Journal of Allergy and Clinical Immunology Abbreviated Journal J Allergy Clin Immunol  
  Volume 138 Issue 1 Pages 47-56  
  Keywords Chronic inflammation; biodiversity; environment; epigenetics; immune dysregulation; metabolism; stress  
  Abstract Recent research indicates that chronic inflammatory diseases, including allergies and autoimmune and neuropsychiatric diseases, share common pathways of cellular and molecular dysregulation. It was the aim of the International von-Behring-Rontgen Symposium (October 16-18, 2014, in Marburg, Germany) to discuss recent developments in this field. These include a concept of biodiversity; the contribution of urbanization, lifestyle factors, and nutrition (eg, vitamin D); and new mechanisms of metabolic and immune dysregulation, such as extracellular and intracellular RNAs and cellular and mitochondrial stress. Epigenetic mechanisms contribute further to altered gene expression and therefore to the development of chronic inflammation. These novel findings provide the foundation for further development of preventive and therapeutic strategies.  
  Address Institute of Laboratory Medicine and Pathobiochemistry, Molecular Diagnostics, University of Marburg, Marburg, Germany. Electronic address:  
  Corporate Author Thesis  
  Impact Factor 11,476 First Author Garn, H. Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Senior Author Renz, H.  
  ISSN 0091-6749 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:27373325 Approved no  
  Call Number Serial 326  
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