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Author Kristensen, J.K.; Karlsmark, T.; Bisgaard, H.; Sondergaard, J. url  openurl
  Title New parameters for evaluation of blood flow in patients with leg ulcers Type Journal Article
  Year (down) 1986 Publication Acta Dermato-Venereologica Abbreviated Journal Acta Derm Venereol  
  Volume 66 Issue 1 Pages 62-65  
  Keywords Adult; Aged; Blood Flow Velocity; Blood Pressure; Humans; Leg Ulcer/*physiopathology; Middle Aged; Rheology  
  Abstract Three new parameters have been introduced to provide data for quantitative evaluation of peripheral cutaneous blood flow in patients with leg ulcers. Reactive hyperemia was induced by occlusion of the blood flow for four minutes at the thigh-level. Blood flow was subsequently measured by laser-Doppler velocimetry in an unselected group of 14 patients with leg ulcers and a matched control group. The parameters used for evaluation was: 1) “peak flow” f(p), 2) divided by time to “peak flow” t(p), rendering a rate constant k (k = f(p)/t(p)) expressing the ability to increase blood flow abruptly in case of need. These parameters were all significantly reduced in the patients with leg ulcers, indicating that this simple and atraumatic technique was useful for discriminating blood flow values that may be relevant for healing time and with a sensitivity comparable to the measurements of distal systolic blood pressure. Distal systolic blood pressure measurements can still be considered to be of value when screening for arterial insufficiency in patients with leg ulcers. The values obtained were significantly lower in 36 patients with leg ulcers compared with 9 age-matched control persons.  
  Address  
  Corporate Author Thesis  
  Impact Factor 03,025 First Author Kristensen, J.K. Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Senior Author Sondergaard, J.  
  ISSN 0001-5555 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:2424219 Approved no  
  Call Number Serial 294  
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