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Author Bisgaard, H.; Olsson, P.; Bende, M. url  openurl
  Title Leukotriene D4 increases nasal blood flow in humans Type Journal Article
  Year (down) 1984 Publication Prostaglandins Abbreviated Journal Prostaglandins  
  Volume 27 Issue 4 Pages 599-604  
  Keywords Administration, Topical; Dose-Response Relationship, Drug; Humans; Lasers; Nasal Mucosa/*blood supply; Regional Blood Flow/drug effects; Rheology; SRS-A/administration & dosage/*pharmacology  
  Abstract The effect of leukotriene D4 on the nasal mucosal blood flow in humans was measured using a laser doppler flow meter. The leukotriene solution was applied topically to the nasal mucosa in 9 healthy subjects, and changes in blood flow were measured non-traumatically by the laser doppler instrument. The response showed a consistent increase in blood flow. A dose-response was found in the range of 0.063 – 4.0 nanomole. These results confirm an earlier study on the human skin, implicating leukotriene D4 as an important vasodilator in humans. No increase in nasal secretion was noted by the subjects tested.  
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  Corporate Author Thesis  
  Impact Factor 02,377 First Author Bisgaard, H. Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Senior Author Bende, M.  
  ISSN 0090-6980 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:6233637 Approved no  
  Call Number Serial 280  
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