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Author Bisgaard, H.; Ford-Hutchinson, A.W.; Charleson, S.; Taudorf, E. url  openurl
  Title Detection of leukotriene C4-liked immunoreactivity in tear fluid from subjects challenged with specific allergen Type Journal Article
  Year (down) 1984 Publication Prostaglandins Abbreviated Journal Prostaglandins  
  Volume 27 Issue 3 Pages 369-374  
  Keywords Adult; Aged; *Allergens; Cross Reactions; Female; Humans; Immune Sera; Male; Middle Aged; *Poaceae; Radioimmunoassay/methods; Rhinitis, Allergic, Seasonal/*immunology; SRS-A/*analysis; Tears/*analysis/immunology  
  Abstract Tear fluid was obtained from allergic subjects from control eyes and eyes challenged with specific allergen and levels of leukotriene C4 (LTC4)-immunoreactivity determined by radioimmunoassay. Formal identification of the leukotrienes released was not possible but the levels of LTC4-immunoreactive material in allergen-challenged tear fluid (4.9 +/- 2.3 ng/ml, n = 9) were significantly higher (p less than 0.01) than those in control tear fluid (0.07 +/- 0.06 ng/ml, n = 9). These results provide evidence that leukotrienes, which account for the biological activity of slow reacting substance of anaphylaxis, may be released in allergic reactions in vivo in man.  
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  Impact Factor 02,377 First Author Bisgaard, H. Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Senior Author Taudorf, E.  
  ISSN 0090-6980 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:6729144 Approved no  
  Call Number Serial 279  
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