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Author Lerche, A.; Bisgaard, H.; Kassis, V.; Christensen, J.D.; Sondergaard, J. url  openurl
  Title Prostaglandin E1 and prostaglandin F2 alpha in exudate in nickel allergy Type Journal Article
  Year (down) 1989 Publication Acta Dermato-Venereologica Abbreviated Journal Acta Derm Venereol  
  Volume 69 Issue 3 Pages 253-256  
  Keywords Adult; Cell Movement; Dermatitis, Contact/immunology/*metabolism; Dinoprost/*metabolism; Dinoprostone/*metabolism; Exudates and Transudates/metabolism; Female; Humans; Hypersensitivity, Delayed/metabolism; Leukocytes; Male; Middle Aged; Nickel/*immunology  
  Abstract Ten nickel-allergic patients and 5 healthy control subjects participated in a study of the kinetics of the flux and concentration of migrated leukocytes and extracellular PGE1 and PGF2 alpha during a 48 h period, using a skin chamber technique. The patients were provided with two skin chambers, one with and one without nickel challenge. A higher flux of leukocytes, PGE1 and PGF2 alpha was observed during the second day of allergen exposure, while the concentrations probably due to dilution were unchanged or diminished, indicating an unspecific role of the prostaglandins during the contact allergic reaction. No correlations were found within the groups between the migration of leukocytes and the prostaglandin content.  
  Address Department of Dermatology, Bispebjerg Hospital, Copenhagen, Denmark  
  Corporate Author Thesis  
  Impact Factor 03,025 First Author Lerche, A. Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Senior Author Sondergaard, J.  
  ISSN 0001-5555 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:2566235 Approved no  
  Call Number Serial 238  
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