The COPSAC2010 cohort
The COPSAC2010 mother-child cohort is a population based longitudinal clinical study of 736 pregnant women and their 700 children. It is the overriding objective to reduce the burden of disease from asthma and other wheezy disorders, eczema and allergy in young children and the long term impact to humans and society. The COPSAC2010 study builds on the comprehensive experience and knowledge gained from the COPSAC2000 mother-child cohort, which has been monitored closely since 1998. Building the novel COPSAC2010 mother-child cohort, we utilized the same standard operating procedures, infrastructure and skilled personnel, assuring the clinical aspects of the study goals will be achieved. The families are monitored closely from week 24 of mothers pregnancy. A major effort is the detailed clinical phenotyping and assessments of genetics, immunology and microbiology.