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“When I was a child, my doctor gave me a note for the school, saying that I should not play football. All I could do was watch the others. Not being able to do the same things as your classmates clearly affects you.”

Like many other children with asthma, Hans Bisgaard experienced its physical and psychological effects. This is one reason why he has dedicated the past 35 years to examining the causes of childhood asthma and to improving the treatment of children with asthma.

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The purpose of the forthcoming international research project is to investigate how dietary supplements and diet during pregnancy and in early life shape the child’s metabolic profile, and how this is linked to asthma and neurological development.

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The COPSAC study with its translational clinical research approach based on long-term studies of mother-child cohorts with deep phenotyping and exposure assessment, combined with genotyping and sequencing of the microbiome, insight into the genetic regulation of basic biological processes, and state-of-the-art systems biology methods holds the promise to improve our understanding of the processes causing disease in individual patients and the interaction between heredity and environment.

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